Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke
University of Kansas Medical Center
Summary
This study is being done to compare outcomes after surgery for individuals who receive anesthesia through by inhaling medication and individuals who receive anesthesia intravenously by needle when experiencing treatment for their stroke. Currently very little is known about the outcomes for patients when comparing these two techniques of providing anesthesia during surgery. This study will provide information regarding outcomes that will help health care providers decide which technique will be better for patients
Description
According to the National Center for Health Statistics, stroke is a leading cause of disability and in 2021 the number five cause of death in the United States1. Endovascular thrombectomy for patients experiencing acute ischemic stroke from the occlusion of a larger cerebral vessel has become a mainstay of treatment.2 Patients undergoing thrombectomy have significantly reduced disability when compared to patients who do not receive this therapy. Several studies have compared outcomes of patients receiving local anesthesia only or sedation versus general anesthesia during endovascular thrombect…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * \>18 years Acute ischemic stroke requiring endovascular treatment. Exclusion Criteria: * \<18 years * Pregnant patients * Patients with malignant hyperthermia * Allergies or any contraindications to either inhalational or intravenous agents * Patients already on intravenous anesthetic infusions * Prisoners * Students and employees
Interventions
- ProcedureAnesthesia drugs during the surgery
During treatment for acute ischemic stroke, patients will be given either inhalation or intravenous anesthesia.
Location
- University of Kansas Medical CenterKansas City, Kansas