A Maximal Use Trial of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa
Incyte Corporation
Summary
The purpose of this study is to evaluate the maximal use of ruxolitinib cream in adult and adolescent participants with hidradenitis suppurativa.
Eligibility
- Age range
- 12–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Diagnosis of HS for at least 6 months before screening visit. * Diagnosis of HS (Hurley Stage I, II, III) with a total abscess and inflammatory nodule count of at least 4 and affecting at least 3 distinct anatomical areas at screening and Day 1 visits. * Total estimated treatment BSA \> 20% at screening and baseline. * Agreement to not use topical or systemic antibiotics for treatment of HS during the Maximal Use Treatment Period. * Willingness to avoid pregnancy or fathering children based on the criteria defined in the protocol. * Further inclusion criteria apply. Exc…
Interventions
- DrugRuxolitinib Cream
Ruxolitinib cream applied topically to the affected area as a thin film twice daily.
Locations (24)
- Saguaro DermatologyPhoenix, Arizona
- First Oc DermatologyFountain Valley, California
- Amicis Research Center ValenciaNorthridge, California
- Children'S Hospital of Orange CountyOrange, California
- Clinical Trials Research InstituteThousand Oaks, California
- Clarity DermatologyCastle Rock, Colorado