McMaster University
The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.
Inclusion Criteria: \- Must be a member of the research expedition team travelling to the Barcroft Research Station in White Mountain California Exclusion Criteria: * BMI \> 30 * No prescribed medications (oral contraceptives excluded) * History of smoking * Currently following a ketogenic diet or consuming exogenous ketogenic supplements * History of heart, lung, blood vessel, or kidney disease * Currently pregnant
0.6 g KME per kg body mass; \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate. (Delta G Ketone, TΔS, Oxford).
Inert, calorie-free placebo drink that is taste-matched to the ketone monoester supplement
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