Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy: A Pilot Feasibility Clinical Trial
University of California, Irvine
Summary
New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management. The SMART pilot trial will test a new mobile health intervention that facilitates remote adherence and symptom monitoring, patient-provider communication outside of clinic visits regarding the use of oral anticancer treatments, and support for financial and social needs, as well as health literacy support, for 30 English- and Spanish-speaking patients. This study will increase understanding of barriers and facilitators to the use of the proposed mHealth intervention.
Description
New oral anticancer treatments (OATs) have improved survival across cancer types but introduced challenges in medication adherence and symptom management. While OATs offer convenience and at-home treatment, they involve complex dosing, drug interactions, and adverse effects requiring careful self-management, and their high out-of-pocket costs can cause financial hardship, hence resulting in suboptimal adherence. Interventions to improve OAT adherence have had mixed results. Given the widespread use of mobile technology, mobile health (mHealth) options offer scalable solutions for medication ma…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Must speak English or Spanish * Must be 18 years of age or older * Have a diagnosis of any type and stage of cancer * Have a new prescription for an oral anticancer therapy (OAT) initiated within the last 90 days or planned to start within the next 15 days * Be receiving treatment at UCI Chao Family Comprehensive Cancer Center-affiliated oncology clinics * Own a smartphone and be willing to receive study-related text messages. Exclusion Criteria: * Have an Eastern Cooperative Oncology Group (ECOG) performance status greater than 2 * Be medically or cognitively unable t…
Interventions
- BehavioralSMART Intervention using TAPPT® for Adherence, Symptom, Financial, and Social Needs Monitoring
The SMART intervention uses TAPPT® smart labels and a web-based app for real-time monitoring of oral anticancer therapy adherence. It includes personalized text reminders, biweekly surveys for medication adherence and symptom burden, missed and extra dose management, symptom alerts to providers, monthly financial and health-related social needs screening with tailored resources, and educational texts for low health literacy. TAPPT® smart labels work with Android/iOS smartphones. All participants receive usual oncology care.
Locations (5)
- Chao Family Comprehensive Cancer Center and Ambulatory Care buildingIrvine, California
- UCI Health Cancer Center - NewportNewport Beach, California
- UCI Health Pacific Breast Care CenterNewport Beach, California
- UCI Health Chao Family Comprehensive Cancer CenterOrange, California
- UCI Health - Yorba LindaYorba Linda, California