A Randomized, Crossover, Controlled Trial Investigating the Effects of Different Cranberry-Based Beverages on Postprandial Glucose, Insulin, and GLP-1
Ocean Spray Cranberries, Inc.
Summary
The goal of this clinical trial is to determine postprandial responses to fruit juices.
Description
Fruit juice is commonly consumed as a part of a balanced diet because of hydration, flavor, and nutrient content . Dietary Guidelines for Americans 2020-2025 recognizes 100% fruit juice as a nutrient-dense beverage that can contribute to fruit and nutrient intake . Liquid form of juices may lead to faster absorption and hormonal responses . Measuring these acute metabolic responses can help clarify the role of fruit juice in dietary patterns and metabolic health .
Eligibility
- Age range
- 18–45 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. ≥18 to ≤45 years of age at Visit 1. 2. BMI ≥18.5 and \<30.0 kg/m2 at Visit 1. 3. Fasting capillary glucose ≤110 mg/dL at Visit 1. 4. Willing to avoid consuming high-polyphenol containing foods for 48 hours prior to each test visit. 5. Willing to abstain from alcohol consumption for 24 hours prior to each study visit. 6. Non-user of tobacco or nicotine products (e.g., cigarette smoking, vaping, chewing tobacco) within 12 months of Visit 1, with no plans to begin use during the study period. 7. Non-habitual users (i.e., daily or almost daily) of marijuana or hemp products…
Interventions
- Dietary SupplementBeverage 1
Fruit juice with zero sugar
- Dietary SupplementBeverage 2
Fruit juice with low sugar - formulation 1
- Dietary SupplementBeverage 3
Fruit juice with low sugar - formulation 2
- Dietary SupplementBeverage 4
Fruit juice with full sugar
- Dietary SupplementBeverage 5
Fruit juice with full sugar
- Dietary SupplementBeverage 6
Glucose control beverage
Location
- Biofortis Innovation ServicesAddison, Illinois