Food Intake and Thermogenesis in High Spinal Cord Injury
University of Miami
Summary
The purpose of this research is to determine the effects of food on cardiovascular and metabolic health in men with and without spinal cord injury (SCI).
Eligibility
- Age range
- 18–65 years
- Sex
- Male
- Healthy volunteers
- Yes
Inclusion Criteria: SCI and Controls * Men * Physically inactive (\<150 minutes per week of moderate-vigorous activity intensity for the preceding 3 months) * Weight stable: body mass ±3 kilograms (kg) for past 3 months SCI Only * Chronic SCI (≥ 1-year post-injury) * Motor-complete SCI American Spinal Injury Association Impairment Scale (AIS) A and B * T6 injuries and above that can independently feed themselves Exclusion Criteria: SCI and Controls * Uncompensated thyroid disease * Diabetes * Swallowing or gastrointestinal pathologies * Allergies or aversions to foods/ingredients * Pres…
Interventions
- OtherLow meal condition
Participants will consume a standardized meal (500 grams) with a low nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours
- OtherModerate meal condition
Participants will consume a standardized meal (500 grams) with a moderate nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours.
- OtherHigh meal condition
Participants will consume a standardized meal (500 grams) with a high nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours.
- OtherAd-libitum control condition
The ad-libitum meal consists of 600-700 g of a standardized control meal one time at all visits. Participants will attend one visit per week for 3 weeks. Each visit is separated by one week and each visit will take approximately 6 hours.
Location
- University of Miami - Miami Project to Cure ParalysisMiami, Florida