A Phase 3b/4 Multi-center, Randomized, Open-label, Long-term Safety Study of Deucravacitinib in Comparison to Ustekinumab in Participants With Moderate-to-Severe Plaque Psoriasis
Bristol-Myers Squibb
Summary
A study to evaluate the long-term safety of Deucravacitinib versus Ustekinumab in participants with psoriasis
Eligibility
- Age range
- 40+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Participants with moderate-to-severe plaque psoriasis: 1. Deemed by the Investigator to be a candidate for phototherapy or systemic treatment for psoriasis, including ustekinumab; 2. Have at least 1 of the following cardiovascular risk factors: * Current cigarette smoker * Diagnosis of hypertension * Diagnosis of hyperlipidemia * Diabetes mellitus type 1 or 2 * History of one or more of the following cardiovascular events: Coronary intervention (PCI) or coronary artery bypass grafting (CABG), myocardial infarction (heart attack), cardiac arrest, hospitalization for…
Interventions
- DrugDeucravacitinib
Specified dose on specified days
- DrugUstekinumab
Specified dose on specified days
Locations (357)
- Local Institution - 0088Birmingham, Alabama
- Medical Dermatology Specialists - PhoenixPhoenix, Arizona
- Saguaro Dermatology - PhoenixPhoenix, Arizona
- Omni DermatologyPhoenix, Arizona
- Alliance DermatologyPhoenix, Arizona
- Local Institution - 0322Scottsdale, Arizona