Assessing the Feasibility of Aromatherapy Essential Oil Associated Changes on Nausea in Patients Receiving Infusion in the Ambulatory Setting
City of Hope Medical Center
Summary
This clinical trial tests how well aromatherapy essential oils work to manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting. Current drugs that are given for nausea may cause constipation and fatigue. Therefore, there is interest in exploring complementary therapies, like aromatherapy, that do not carry the same side effects. Using aromatherapy essential oils such as ginger, peppermint, and lavender, may help reduce nausea and anxiety. Some studies have shown significant reductions in nausea and anxiety among cancer patients using these oils, while other studies have had mixed results. Ginger and peppermint oils, in particular, have been associated with helping reduce nausea during chemotherapy, while lavender has shown potential benefits for anxiety. Jojoba oil will be used as a placebo for this research study. Jojoba oil is extracted from the seeds of a jojoba plant, which is a green shrub that is found in the southwestern United States). Jojoba oil is an oil which has no color or smell. Aromatherapy essential oils used through a personal inhalation device during chemotherapy may better manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting.
Description
PRIMARY OBJECTIVES: I. To determine the feasibility of utilizing aromatherapy essential oils during outpatient infusions. II. To assess satisfaction of patients receiving aromatherapy essential oils during outpatient infusions. SECONDARY OBJECTIVES: I. To observe whether aromatherapy essential oils (compared to placebo aromatherapy) influence an increase or decrease in nausea in patients undergoing moderate-risk and a high-risk emetogenic chemotherapy regimen. II. To observe whether aromatherapy essential oils (compared to placebo aromatherapy) influence an increase or decrease in anxiety…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients must have the ability to understand and sign a written informed consent document, and be willing to follow protocol requirements * Ability to read and understand English for patient reported outcomes * Age \>= 18 years * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 * Willingness to comply with all study interventions of essential oil aromatherapy * Have been on a moderate- to high-risk emetogenic chemotherapy regimen as defined by the National Comprehensive Cancer Network (NCCN) for at least 1 cycle of therapy * At least 2 remaining infusio…
Interventions
- ProcedureAromatherapy and Essential Oils
Inhale peppermint oil
- ProcedureAromatherapy and Essential Oils
Inhale lavender oil
- ProcedureAromatherapy and Essential Oils
Inhale ginger oil
- ProcedureAromatherapy and Essential Oils
Inhale placebo jojoba oil
- OtherQuestionnaire Administration
Ancillary studies
Locations (2)
- City of Hope Medical CenterDuarte, California
- City of Hope at Irvine LennarIrvine, California