Study detail
RecruitingPhase 2
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study Evaluating the Efficacy and Safety of EVO756 in Adults With Atopic Dermatitis
Evommune, Inc.
Summary
This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe atopic dermatitis.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Detailed criteria
Inclusion Criteria: * Chronic AD that has been present for ≥6 months * Validated-Investigator's Global Assessment score of ≥3 * EASI of ≥16 * BSA of AD involvement of ≥10% Exclusion Criteria: * Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening * Use of certain medications * Presence of skin comorbidities or other condition(s) that may interfere with study assessments * Significant AD flare, in the opinion of the Investigator, within 4 weeks prior to study entry
Interventions
- DrugEVO756
Dose 1
- DrugEVO756
Dose 2
- DrugEVO756
Dose 3
- DrugPlacebo control
Placebo control
Locations (29)
- Saguaro DermatologyPhoenix, Arizona
- Center for Dermatology Clinical ResearchFremont, California
- Metropolis Dermatology - Downtown Los AngelesLos Angeles, California
- Skin and Beauty CenterPasadena, California
- Skin Care Research, LLCBoca Raton, Florida
- Driven Research, LLCCoral Gables, Florida