The Effect of Spinal Cord Stimulators on Restless Leg Syndrome

Summary

This study aims to evaluate neurophysiological responses and symptom changes in individuals with Restless Legs Syndrome (RLS) and/or chronic pain. Participants will undergo standard clinical assessments including EEG, EMG, h-reflex, SSEP, ERP, and TMS under varying SCS conditions.The study involves 4 arms. Arm 1 are individuals diagnosed with RLS and Healthy Controls. Arm 2 are individuals diagnosed with RLS and have an existing SCS. Arm 3 are individuals diagnosed with RLS and scheduled to receive a SCS. Arm 4 are individuals with chronic pain and have a SCS, but no diagnosis of RLS.

Eligibility

Age range

18+ years

Sex

All

Healthy volunteers

Yes

Interventions

• Other
  H-Reflex

  H-reflex - A small electrical stimulus is provided to the leg and foot area and a measurement of the stimulus is taken by the EEG electrodes.

• Other
  Somatosensory evoked potential (SSEP)

  A small electrical stimulus is provided to a nerve on the body and measured at several places along the nervous system (spinal cord, brain, etc.) with the EMG and EEG electrodes.

• Other
  Vibratory Electrophysiological Response Potential (ERP)

  stimulation is provided to the ankle with vibration sensations using a device like a buzzer and the recording of the body's responses using the EEG and/or EMG electrodes.

• Other
  Transcranial Magnetic Stimulation (TMS)

  A small magnetic pulse is used to provide a small amount of electrical stimulation to the nervous system. The EEG and/or EMG electrodes will be used to measure the body's reaction.

• Other
  Spinal Cord Stimulator (SCS) manipulation

  Spinal cord stimulator will be turned on/off

Location