Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)
University of Virginia
Summary
The purpose of this study is to assess preliminary efficacy of a tailored cognitive bias modification for interpretation (CBM-I) app for reducing anxiety in Huntington's disease and Parkinson's disease.
Description
The investigators will conduct a pilot randomized controlled trial of the MindTrails-Movement CBM-I app in patients with Huntington's disease and Parkinson's disease (N=136). Participants randomly assigned to the intervention group (N=68) will be asked to download the MindTrails-Movement mobile app and to complete daily CBM-I training sessions and nightly surveys, in addition to surveys at baseline and every 2 weeks for the duration of the 6-week intervention and at 4-week follow-up (week 10). Participants assigned to the waitlist control group will download a control version of the app witho…
Eligibility
- Age range
- 21+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Clinical diagnosis of Huntington's disease or Parkinson's disease (genetic diagnosis of HD also acceptable) * With anxiety symptoms (NeuroQoL Anxiety ≥12) Exclusion Criteria: * Cognitive decline precluding ability to consent or complete the intervention (MoCA 5 min/telephone ≤11) * Unable to read and understand English * Does not have regular access to an internet-connected device, capable of downloading and installing the mobile application (i.e., tablet or iPhone running iOS 10 or later or an Android phone running Android 5.0 or later) * Not located in the USA * \<21…
Interventions
- BehavioralMindTrails-Movement
CBM-I training app with active CBM-I training condition
- OtherWaitlist Control
Version of MindTrails-Movement app including surveys and list of support resources but without active CBM-I training component
Location
- Univeristy of Virginia School of NursingCharlottesville, Virginia