A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Enlicitide Decanoate Coadministered With Rosuvastatin in Adults With Hyperlipidemia

Summary

Researchers designed a study medicine called enlicitide to lower low-density lipoprotein cholesterol (LDL-C). In this study, researchers want to learn about giving enlicitide with another medicine called rosuvastatin. Rosuvastatin is a standard (usual) treatment to lower LDL-C. The goal of this study is to learn if enlicitide given with rosuvastatin works better than placebo on lowering LDL-C in a person's blood. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of a study medicine.

Eligibility

Age range

18–64 years

Sex

All

Healthy volunteers

No

Interventions

• Drug
  Enlicitide

  Oral Tablet

• Drug
  Rosuvastatin

  Oral Capsule

• Drug
  Placebo for Enlicitide

  Oral Tablet

• Drug
  Placebo for Rosuvastatin

  Oral Capsule

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