A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

Inclusion Criteria: Participants must meet all inclusion criteria to be eligible for trial participation. 1. Males or females ≥ 50 years of age at the time of signing the informed consent. 2. Diagnosis of HFpEF as defined by European Society of Cardiology or American College of Cardiology/American Heart Association criteria 3. NYHA Functional Class II or III 4. LVEF ≥ 50% demonstrated by echocardiography (ECHO) performed at Screening with evidence of heart failure 5. Elevated NT-proBNP at Screening 6. NordicPRO-C6™ ≥ 11 ng/mL at Screening. 7. Stable dose of all concomitant HF medications for…