Association of Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients: A Large-Scale Retrospective Cohort Analysis
Zeliha Alicikus
Summary
The aim of this retrospective cohort study is to compare the safety and efficacy of induction agents for tracheal intubation in critically ill adult patients.
Description
Endotracheal intubation is an accepted procedure to optimize oxygenation and ventilation and reduce the risk of aspiration for critically ill patients, essential for their management and survival across various settings, including prehospital care, emergency departments (EDs), and intensive care units (ICUs). Despite advancements, peri-intubation complications and hemodynamic instability, which are associated with increased mortality rates, remain a concern. These risks are exacerbated by pathophysiological factors in critically ill patients compared to those undergoing intubation in surgical…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age ≥ 18 years * Admission to the surgical ICU for critical care * Administration of one of the studied induction agents * Availability of complete clinical data Exclusion Criteria: * Age \< 18 years * Absence of documented induction agent administration * Incomplete or missing medical records
Interventions
- Procedureinduction type for intubation in ICU
Clinical data documented throughout the course of hospitalization will be retrieved and analyzed.
Location
- UF Health Jacksonville (Shands Hospital)Jacksonville, Florida