Closed Loop Oxygen Control in COPD Patients Treated With Nasal High Flow in the Hospital
Fisher and Paykel Healthcare
Summary
The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with hypoxemia/respiratory distress.
Eligibility
- Age range
- 22+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Has cognitive ability to provide informed consent * Aged 22 years or older * Hospitalized with hypoxemia/respiratory distress * Diagnosis of COPD * Candidate for/currently prescribed nasal high flow (flow rate of at least 25 L/min) with supplemental oxygen, as assessed by the investigator * Expected duration of oxygen and nasal high flow therapy \>24 hours (not necessarily continuous) Exclusion Criteria: * Receiving Non Invasive Ventilation (NIV) or indicated for NIV as per European Respiratory Society /American Thoracic Society guidelines * Hemodynamic instability (sy…
Interventions
- DeviceClosed loop oxygen control
Nasal high flow with closed loop oxygen control
- DeviceManual titration
Nasal high flow with manual titration
Locations (3)
- Central Iowa Hospital Corp - UnityPoint HealthDes Moines, Iowa
- Icahn School of Medicine at Mount SinaiNew York, New York
- Temple University HospitalPhiladelphia, Pennsylvania