A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer
Children's Hospital Medical Center, Cincinnati
Summary
The goal of this clinical trial is to learn if a tailored intervention can help make it easier for adolescents and young adults with cancer to take their medications. The main questions the researchers are trying to answer are: * Does the tailored intervention increase adherence? * Does the tailored intervention improve quality of life? * Does the tailored intervention reduce health care utilization? The researchers will compare the tailored intervention to a uniform standard of care intervention (an intervention designed to be similar to what is currently happening in clinical care) to see if the tailored intervention works to improve adherence. Participants will: * Use an electronic pill bottle or box to store their medication * Participate in intervention sessions * Complete surveys before the intervention, after the intervention, and 6-months later
Description
The proposed research includes a randomized clinical trial of a tailored adherence-promotion intervention (Tailored Program) as compared to uniform standard of care (Feedback Program) for adolescents and young adults with cancer. As part of this study, up to 160 adolescents and young adults (AYAs) with cancer will be randomized to one of these groups. Participants who enroll in this trial will be given an electronic pill bottle or box with a computer chip to store their medication. After using the electronic monitor for a few weeks to assess baseline adherence, participants who demonstrate non…
Eligibility
- Age range
- 15–24 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patient is 15.00 to 24.99 years of age * Patient is diagnosed with cancer * Patient is prescribed an oral anticancer/antitumor agent or prophylaxis Exclusion Criteria: * Patient is not fluent in English * Patient evidences significant cognitive deficits * Patient's medical status or treatment precludes participation * Patient enrolled on a medical trial requiring medication storage in a trial-provided container * Patient demonstrates greater than or equal to 95% adherence during run-in period * Patient declines to use or has difficulty using electronic adherence monito…
Interventions
- BehavioralTailored Program
Participants will participate in 4 sessions with a coach, 1 every other week. During these sessions, the participant will work with their coach to identify a barrier to adherence they would like to target. Then, they will work with their coach to create an action plan using evidence-based behavior change techniques to address this barrier. In between sessions (on alternating weeks), the coach will check-in with a text reminder about the plan.
- BehavioralFeedback Program (Uniform Standard of Care)
Participants will receive weekly text messages with feedback about their adherence and guidance for requesting additional support if desired
Locations (4)
- The University of Kansas Medical CenterKansas City, Kansas
- Columbia University Irving Medical CenterNew York, New York
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio
- Seattle Children's HospitalSeattle, Washington