Medical University of South Carolina
This study investigates the safety and potential efficacy of personalized, image-guided low intensity focused ultrasound (LIFU) targeting the thalamus in individuals with Autism Spectrum Disorder (ASD). The study evaluates behavioral, neuroimaging, and electrophysiological outcomes following LIFU stimulation using a non-invasive device.
Inclusion Criteria: * Age 13-25 * Diagnosis of ASD (DSM-5) * Full Scale IQ \> 70 * Verbal communication * Stable medication for ≥1 month * Ability to consent or assent with guardian consent Exclusion Criteria: * MRI or LIFU contraindications * Recent investigational drug/device use * Neurological illness (e.g., epilepsy, TBI) * Substance use disorder * Sensory/motor impairments preventing task completion
In this open label study, all participants will receive active LIFU
Verify or correct the compensation shown for this listing.