Blinded, Randomized, Controlled, Trial to Evaluate the Efficacy and Safety of Autologous Hair Follicle Secretome for Facial Rejuvenation
Acorn Biolabs Inc.
Summary
Secretome treatment for facial rejuvenation
Description
This study will quantitatively evaluate the efficacy and safety of the autologous hair follicle secretome for skin rejuvenation. The secretome is produced by non-invasively collecting hair follicles by plucking 50-75 hairs. Ten follicles are selected to cultured in media (proprietary xeno- and human protein free) for 4 weeks and conditioned media is collected and lyophilized to produce the autologous secretome product. The secretome contains growth factors, extracellular matrix molecules, cytokines, exosomes, etc. Upon use, the autologous secretome is diluted in saline and used on the subject…
Eligibility
- Age range
- 30–70 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria * Male or Female * Age: ≥30 and ≤ 75 at the time of consent. * Fitzpatrick skin types I-V * Moderate to very severe facial aging according to the SASSQ for the categories of elasticity, wrinkles, and skin roughness. * Willing to refrain from cosmetic procedures throughout the study period (i.e. laser treatments, chemical peels, microneedling, dermal filler injections, neuromodulator injections, etc.) * Willing to use study support products as directed and will not introduce any new skin care or makeup products throughout the study period. Subjects will be provided with a Sk…
Interventions
- OtherAutologous Hair Follicle-Derived Secretome
This interventional product is a secretome derived from the stem cells that reside in the hair follicle.
- OtherControl Saline
Saline solution will be the placebo control. The active is diluted with saline so this is an appropriate control.
Location
- Steve Yoelin, MDNewport Beach, California