A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of JNJ-95597528 for the Treatment of Adult Participants With Moderate to Severe Atopic Dermatitis
Janssen Research & Development, LLC
Summary
The purpose of this study is to assess how well JNJ-95597528 works compared to placebo in participants with moderate to severe atopic dermatitis (AD).
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion criteria: * Be otherwise healthy on the basis of physical examination, medical history, vital signs, and 12-lead electrocardiogram (ECG) performed at screening * Meets all the following disease activity criteria: a. Chronic atopic dermatitis (AD), according to American Academy of Dermatology Consensus Criteria with onset of symptoms at least 1 year prior to screening visit; b. Eczema area and severity index (EASI) score greater than or equal to (\>=) 16 at the screening and Week 0; c. validated investigator global assessment for atopic dermatitis (vIGA-AD) score \>= 3 at screening a…
Interventions
- DrugJNJ-95597528
JNJ-95597528 will be administered subcutaneously.
- DrugPlacebo
Placebo will be administered subcutaneously.
Locations (56)
- First OC DermatologyFountain Valley, California
- Southern California DermatologySanta Ana, California
- Driven Research LLCCoral Gables, Florida
- Arlington DermatologyRolling Meadows, Illinois
- Dawes Fretzin Clinical Research GroupIndianapolis, Indiana
- Henry Ford Health SystemDetroit, Michigan