Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation
The University of Texas Health Science Center, Houston
Summary
The purpose of this study is to evaluate whether microneedling RF subcutaneous fat pad thickness in the temple, submental, and cheek regions, to determine whether the addition of topical PLLA after microneedling RF alters or preserves subcutaneous fat pad thickness and to assess patient satisfaction and perceived outcomes following microneedling RF ± PLLA treatment.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Seeking facial rejuvenation for cosmetic concerns * Able and willing to provide informed consent * Willing to comply with study procedures and follow-up visits Exclusion Criteria: * Prior filler injection or energy-based device treatment to the face within the past 6 months * Previous facial surgeries * Pregnant or breastfeeding * Active infection, dermatitis, or open lesions in the treatment area * History of keloids or abnormal scarring * Known allergy to poly-L-lactic acid (PLLA)- Current participation in another clinical trial involving facial aesthetic treatments…
Interventions
- Devicemicroneedling RF treatment
Participants will undergo two microneedling RF treatment sessions, 4-6 weeks apart
- DevicePLLA
Participants will undergo two microneedling RF treatment sessions, 4-6 weeks apart followed by PLLA application after each treatment
- DrugSterile Water as control
Participants will undergo two microneedling RF treatment sessions, 4-6 weeks apart followed by sterile water application after each treatment
Location
- The University of Texas Health Science Center at HoustonHouston, Texas