The Impact of BBTI on Cognition and Sleep Health in Older Adults With HIV
University of Alabama, Tuscaloosa
Summary
The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are: What are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT? Participants will: * Complete 4 weeks of telephone-delivered BBTI or BMT * Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments * Have blood collected at all three time points
Eligibility
- Age range
- 50–99 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * must be age 50 or older * have a DSM-5 diagnostic criteria for insomnia including sleep difficulty that occurs at least 3 times per week and has been a problem for at least 3 consecutive months (indicated on the Structured Clinical Interview for Sleep Disorders, SCISD) during telephone screening * have a confirmed HIV diagnosis and a prescribed ART regimen for at least 12 months. Exclusion Criteria: * unable to speak English * have a reported or documented (in medical records) diagnosis of AD or dementia * have severe neurocognitive impairment (\>7 errors on the Short…
Interventions
- BehavioralBBTI
4-week intervention delivered via telephone (once a week for 30 minutes)
- BehavioralBMT
4-week intervention delivered via telephone (once a week for 30 minutes)
Locations (2)
- The University of Alabama at BirminghamBirmingham, Alabama
- The University of AlabamaTuscaloosa, Alabama