A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Moderate to Severe Atopic Dermatitis
UCB Biopharma SRL
Summary
The purpose of the study is to evaluate the dose-response relationship of galvokimig compared with placebo in study participants with moderate-to-severe atopic dermatitis (AtD).
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Participant must be aged greater than or equal (≥)18 years at the time of signing the informed consent * Participant has chronic atopic dermatitis (AtD) (according to American Academy of Dermatology Consensus Criteria) that has been present for at least ≥1 year prior to initiating the study (ie, signing of the informed consent form \[ICF\]) and with: 1. validated Investigator Global Assessment (vIGA) score ≥3 at Screening and Baseline 2. Eczema Area and Severity Index (EASI) score ≥16 at both Screening and Baseline 3. Peak Pruritus Numerical Rating Scale (PP-NRS)…
Interventions
- BiologicalGalvokimig
Drug: Galvokimig Pharmaceutical form: Solution for injection
- DrugPlacebo
Drug: Placebo Pharmaceutical form: Solution for injection
Locations (57)
- Atd002 52021Oceanside, California
- Atd002 52008Santa Monica, California
- Atd002 52013Boca Raton, Florida
- Atd002 52007Coral Gables, Florida
- Atd002 52003Miami, Florida
- Atd002 52015Savannah, Georgia