Jiangsu HengRui Medicine Co., Ltd.
The ExCIT study is being conducted to evaluate the efficacy, and safety of of Hetrombopag Olamine Tablets Vs Placebo in Patients with Chemotherapy-Induced Thrombocytopenia.
Inclusion Criteria: 1. Male or female, age ≥ 18 years at screening. 2. Histologically or cytologically confirmed solid tumor (e.g., non-small-cell lung carcinoma \[NSCLC\], breast, ovarian, bladder, pancreatic, gastrointestinal, or colon/colorectal cancer). 3. Receiving platinum- and/or gemcitabine-containing chemotherapy regimens on 14- or 21-day treatment cycles. 4. Platelet count \< 85 x 109/L at enrollment. 5. For Part B, experiencing a chemotherapy delay of ≥ 7 days due to CIT. 6. At least 2 scheduled chemotherapy cycles of the same treatment regimen as was used prior to enrollment. 7. E…
For Part A, all participants would receive hetrombopag treatment.
For Part B, participants would be randomized to receive hetrombopag treatment or matching placebo, respectively.