A Phase 1/2 Study of BMS-986525 as Monotherapy and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer
Bristol-Myers Squibb
Summary
The purpose of this study is to assess the safety and tolerability of BMS-986525 alone and in combination with Nivolumab in participants with Relapsed/Refractory Small Cell Lung Cancer
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria * Participants must have histologically or cytologically documented relapsed/refractory small cell lung cancer (R/R-SCLC). * Participants must have received at least 1 platinum-based chemotherapy regimen as per locally approved drug labels and institutional guidelines. * In countries where standard of care first line systemic treatment includes platinum containing chemotherapy in combination with anti-PD-(L)1 therapy, it is required that participants have progressed on, are ineligible for or not have access to an anti-PD- (L)1 therapy. Exclusion Criteria * Participants mu…
Interventions
- DrugBMS-986525
Specified dose on specified days
- DrugNivolumab
Specified dose on specified days
Locations (11)
- Local Institution - 0011Detroit, Michigan
- Local Institution - 0026Buffalo, New York
- Duke Cancer InstituteDurham, North Carolina
- University Hospitals Cleveland Medical CenterCleveland, Ohio
- SCRI Oncology PartnersNashville, Tennessee
- Local Institution - 0001Rozzano, Milano