ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.
Bristol-Myers Squibb
Summary
A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Cancer (NSCLC)
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria * Participants must have a histologically- or cytologically-confirmed diagnoses of non-small cell lung cancer (NSCLC) with unresectable Stage III disease. * Participants must have received at least 2 cycles of platinum-based concurrent chemoradiotherapy (a total dose of radiation of at least 54 Gy). * Participants must have no progressive disease (PD) following treatment with concurrent chemoradiotherapy (CCRT). * Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1. Exclusion Criteria * Participants with non-squamous…
Interventions
- DrugPumitamig
Specified dose on specified days
- DrugDurvalumab
Specified dose on specified days
Locations (254)
- Southern Cancer Center PcDaphne, Alabama
- Local Institution - 0780Chandler, Arizona
- Local Institution - 0585Golden, Colorado
- Medical Oncology Hematology Consultants, PANewark, Delaware
- Local Institution - 0711Ocala, Florida
- Local Institution - 0756Marietta, Georgia