Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.
University of Miami
Summary
This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.
Eligibility
- Age range
- 50–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Parkinson's Disease Hoehn \& Yahr Stages 1-3 * Able to walk 50m unassisted * Able to understand and communicate in English * A Montreal Cognitive Assessment (MoCA) score above 18 Exclusion Criteria: * Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program * Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness * Unresolved injury or surgery to the upper or lower limbs that prevents weight training.
Interventions
- BehavioralLow-Load Resistance Training
Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.
- BehavioralHigh-Load Resistance Training
Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.
Location
- Laboratory of Neruomuscular Research and Active AgingCoral Gables, Florida