Feasibility of a Novel Oral Palatable Elemental Diet for Gastrointestinal Symptoms in Chronic Pancreatitis
Stanford University
Summary
The goal of this clinical trial is to learn whether a 2-week exclusive palatable elemental diet is feasible, tolerable, and acceptable for adults with chronic pancreatitis and bothersome gastrointestinal symptoms. An elemental diet is a nutritionally complete formula made from ingredients that are easy to absorb. The main questions it aims to answer are whether participants can complete the diet as planned and whether they can take in most of the prescribed formula.
Eligibility
- Age range
- 18–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adults aged 18 to 75 years * Clinical diagnosis of chronic pancreatitis based on medical history and study physician assessment * Self-reported chronic pancreatitis-related gastrointestinal symptoms within 30 days before enrollment, with significant global gastrointestinal symptom burden defined as a Structured Assessment of Gastrointestinal Symptoms (SAGIS) score of 16 or higher Exclusion Criteria: * Pancreatic tumor or pancreatic cancer * History of pancreatic surgery * Pregnancy or breastfeeding * Diagnosis of a condition other than chronic pancreatitis that contrib…
Interventions
- OtherPalatable Elemental Diet
The intervention is an exclusive oral palatable elemental diet administered for 14 consecutive days as the participant's sole nutritional intake. This amino acid-based formula was developed to provide an elemental diet with improved palatability and tolerability. Following completion of the 14-day diet period, participants will return to their usual diet and undergo 4 additional weeks of follow-up.
Location
- Stanford Digestive Health Care CenterRedwood City, California