Early-Onset Colorectal Cancer Patients Too Young for Screening: Outcomes and Treatment Patterns
Methodist Health System
Summary
This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
Description
Specifically, investigator want to investigate the effect of having a diagnosis of CRC before the age of 35 years on:disease stage at presentation, insurance status at diagnosis, treatment patterns by stage, and adjusted cancer-specific survival. The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy.
Eligibility
- Age range
- 35+ years
- Sex
- All
- Healthy volunteers
- Not specified
Inclusion Criteria: * Colorectal cancer Exclusion Criteria: * No Colorectal cancer
Interventions
- OtherColorectal cancer
CRC is a disease that is often associated with older adults (\<50 years). CRC remains the second most common cause of cancer death in males and the third most common cancer death in women. Despite this, CRC incidence has steadily declined in older adults; however, there is a concerning rise of incidence of colorectal cancer in young patients. The incidence of CRC in men and women under the age of 50 steadily increased 2.1 percent per year from 1992 through 2012.
Location
- Methodist Dallas Medical Center- Clinical Research InstituteDallas, Texas