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Phase 1

A Phase 1b Trial in Relapsed/Refractory Small Cell Lung Cancer to Determine the Clinical Activity, Safety Profile, and Pharmacology of ST-001, a Fenretinide Phospholipid Suspension (12.5 mg/mL) for Intravenous Infusion

This study evaluates a fenretinide phospholipid suspension for the treatment of small cell lung cancer (SCLC).

Small Cell Lung Cancer

Estimated

~$10 – $8,750

SciTech Development, Inc.NCT06922539

Phase 3

A Randomized Pivotal Study Assessing the Safety and Efficacy of Targeted Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound During the Standard of Care Treatment of Brain Metastases of Non-small Cell Lung Cancer (NSCLC) Origin

The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier opening with Exablate Model 4000 Type 2.0/2.1 for the treatmen…

Brain TumorNon Small Cell Lung Cancer

Respiratory Muscle Training During Cancer Treatment: Effects on the Autonomic Nervous System and Cardiotoxicity

This clinical trial evaluates whether home-based respiratory muscle training is useful for minimizing side effects in patients undergoing treatment for cancer.…

Breast CarcinomaHead and Neck CancerLung Cancer

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT05787834

Phase 1

A Phase IB, Single Dose, Open-Label, Dose-escalation Study to Investigate the Safety and Imaging Characteristics of Pemefolacianine for Intraoperative Molecular Imaging of Lung Cancer

The aim of this Phase 1b study is to investigate the safety and fluorescence signal of a single dose of Pemefolacianine for Injection, a novel fluorescence ima…

Lung Cancer (Locally Advanced or Metastatic)

Estimated

~$10 – $7,500

Sunil SinghalNCT07772895

Phase 2

Ph 2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab and Nivolumab With or Without Docetaxel Versus Docetaxel in 2L Treatment of Participants With Metastatic NSCLC (GDFATHER-NSCLC-02)

This is an exploratory, signal-finding, randomized, placebo-controlled, blinded, multi-center phase 2b trial of the anti-GDF-15 antibody Visugromab (CTL-002) a…

Metastatic Non-Squamous Non-Small Cell Lung CancerAdult Solid Tumor

Estimated

~$10 – $8,750

CatalYm GmbHNCT07246863

Phase 1

Phase I/II Study of the Selective RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Pha…

RET-altered Non Small Cell Lung CancerRET-altered Solid Tumors

Estimated

~$10 – $8,750

Taiho Pharmaceutical Co., Ltd.NCT04683250

Phase 1

A Phase 1 and 2 First-in-human, Open-label, Multicenter Study to Assess the Safety, Tolerability and Preliminary Efficacy of VMD-102 in Participants With Hepatocellular Carcinoma and Other Advanced Solid Tumors

This study is to evaluate the safety and tolerability to determine (i) the recommended Phase 2 dose (RP2D) of VMD-102 (Phase 1), and (ii) preliminary anti-tumo…

Hepatocellular Carcinoma (HCC)Metastatic Uveal MelanomaRenal Cell Carcinoma (RCC)+2 more

Estimated

~$10 – $8,750

VM Discovery, Inc.NCT07636785

Phase 1

A Phase I/II Open-label Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD6750, a CD8 Guided IL-2 Agent Alone and in Combination With Other Anti-cancer Agents in Participants With Select Advanced or Metastatic Solid Tumors

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+6 more

Estimated

~$10 – $7,500

AstraZenecaNCT07115043

Phase 2

A Phase II Trial of GT103 in Combination With Pembrolizumab in STK11 Mutant Non-Small Cell Lung Cancer (NSCLC)

This phase II trial tests how well GT103 in combination with pembrolizumab works in treating patients with STK11 mutant non-small cell lung cancer that may hav…

Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+1 more

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT07017829

Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization: A Single-Center Prospective Diagnostic Accuracy Study

This study evaluates whether multiparametric chest magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), performed without any contrast mater…

Solitary Pulmonary NoduleMultiple Pulmonary NodulesLung Neoplasms+1 more

Estimated

~$10 – $750

University of FloridaNCT07768046

Phase 2

KEYMAKER-U01 Substudy 01G: A Phase 2, Umbrella Study With Rolling Arms of Investigational Agents in Combination With Pembrolizumab With or Without Platinum-based Chemotherapy in Treatment-Naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC)

Researchers are investigating new treatments for untreated advanced non-small cell lung cancer (NSCLC), which is the most common form of lung cancer and lung c…

Non-small Cell Lung Cancer

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06731907

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk For Cancer

This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or…

Cancer RiskCancer Predisposition SyndromeHereditary Cancer Prediction+28 more

Estimated

~$10 – $1,125