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Phase 2
A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of DCR-PHXC in Patients With Primary Hyperoxaluria Type 1 and Severe Renal Impairment, With or Without Dialysis
The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyNCT04580420
Rare Kidney Stone Consortium Registry for Hereditary Kidney Stone Diseases
The purpose of this study is to collect medical information from a large number of patients in many areas of the world with primary hyperoxaluria (PH), Dent di…
Primary HyperoxaluriaDent DiseaseCystinuria+1 more
Mayo ClinicNCT00588562
Rare Kidney Stone Consortium Biobank, Rare Diseases Clinical Research Network
This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent…
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo ClinicNCT02026388
Phase 1
A Phase 1/2 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ABO-101 in Participants With Primary Hyperoxaluria Type 1 (PH1)
The goal of the redePHine study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABO-101 in participants with primary hyperox…
Primary Hyperoxaluria Type 1 (PH1)
Arbor BiotechnologiesNCT06839235