Human Epilepsy Genetics--Neuronal Migration Disorders Study
Harvard University Faculty of Medicine
Summary
The purpose of this study is to identify genes responsible for epilepsy, brain malformations and disorders of human cognition.
Description
Epilepsy is responsible for tremendous long-term healthcare costs. Analysis of inherited epilepsy conditions has allowed for identification of several key genes active in the developing brain. Although many genetic abnormalities of the brain are rare and lethal, rapidly advancing knowledge of the structure of the human genome makes it a realistic goal to identify genes responsible for other epileptic conditions, related brain malformations and disorders of cognition. The purpose of this study is to identify genes responsible for epilepsy and disorders of human cognition (EDHC). The Walsh Labo…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- No
INCLUSION: * Males and females of any age. * Persons with a brain malformation or disorder of cognition (familial intellectual disability \[previously known as mental retardation\] or autism). EXCLUSION: * Persons without a brain malformation or disorder of cognition (familial intellectual disability (previously known as mental retardation\] or autism).
Location
- Boston Children's Hospital, Walsh LaboratoryBoston, Massachusetts