Auricular Vagal Nerve Stimulation for Gastric and Brain Outcomes
Massachusetts General Hospital
Summary
This study will determine how noninvasive nerve stimulation affects human brain, stomach, and autonomic activity.
Description
Scientific research into the basic mechanisms underlying neuromodulation is relatively recent and incomplete. The purpose of the proposed study is to determine how a form of neuromodulation, transcutaneous electro-accupoint stimulation, which is non-invasive and non-painful, affects human brain, stomach, and autonomic activity. We will accomplish this by integrating whole brain functional MRI (fMRI) methodologies with gastric MRI and physiological monitoring. This study will comprise 3 functional magnetic resonance imaging (fMRI) brain-gut scans, all while receiving the neuromodulation with v…
Eligibility
- Age range
- 18–65 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Adults 18-65 * Functional dyspepsia Exclusion Criteria: * Any condition contraindicating an fMRI brain scan
Interventions
- Deviceactive TEAS
non-painful active transcutaneous electro-acupoint stimulation will be delivered to the abdomen and leg
Location
- Massachusetts General HospitalBoston, Massachusetts