Physiological Brain Atlas Development
Vanderbilt University Medical Center
Summary
The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume. This initially was used to improve DBS implants for Parkinson's Disease, Dystonia, Essential Tremor, and OCD, but now includes data acquired during all stereotactic brain procedures.
Description
Purpose: 1. To create a brain atlas that will allow physiological and clinical information to be assigned to anatomical locations in MRI space, utilizing non-rigid MRI normalization algorithms. These data will specifically be acquired from the population of patients undergoing stereotactic brain procedures. 2. To collate and analyze the brain data placed in the atlas in a statistical manner that allows doctors to understand and treat brain disease more precisely and based on population data. For example, this would allow surgeons to predict optimal targeting locations for DBS implants, neurol…
Eligibility
- Age range
- 6–90 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * All patients who are recommended for Stereotactic Brain procedures * Any patient who has agreed to undergo a Stereotactic Brain procedure * Patients age under 6 -90 years old Exclusion Criteria: * Patients who fail recommendation for Stereotactic Brain procedures * Patients not consented for Stereotactic Brain procedures * Patients outside the age range of 6 -90 years old * Patients or legal guardians not able to provide informed consent
Interventions
- DeviceStereotactic brain procedures
Stereotactic brain procedures
Location
- Vanderbilt UniveristyNashville, Tennessee