Weill Medical College of Cornell University
The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.
Procedure: The patient will undergo preoperative sonographic assessment of both ovaries to determine if either ovary is diseased or compromised. Patient will undergo preoperative blood sampling to measure AMH, FSH, LH and estradiol as indicators of current ovarian function (less than 8 teaspoons) if time allows and assessment of ovarian reserve is appropriate; menopausal levels of FSH (≥ 30 miu/ml) will be a contraindication to participation in this study. The patient may have infectious disease testing as part of the evaluation for fertility preservation treatment. Patient will undergo preope…
Inclusion Criteria: * Females 0-45 years of age who are premenopausal * Treatment plan that will likely result in premature menopause or premature ovarian failure * This includes patients receiving: * Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy * Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients * Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos. * Previous treatment for cancer is acceptable if patient still has ovarian function * Patient…
oophorectomy to remove a disease ovary.
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