Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
Massachusetts General Hospital
Summary
In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.
Description
Once you are enrolled in the study, you will receive treatment, evaluations and follow up care for your type of cancer as determined by your treating physician according to clinical judgment and standard of care for your clinic. All treatments that you receive will be recorded, including all surgeries and chemotherapy given before or after PBRT. Treatment outcomes, like how you respond to treatment, side effects, and progression of your cancer will be collected as the information becomes available. A study coordinator or research nurse at your clinic will perform a chart review annually to upd…
Eligibility
- Age range
- Up to 21 years
- Sex
- All
- Healthy volunteers
- No
Eligibility Criteria: 1. Patients treated with radiation therapy at one of the participating centers 2. Age \< 22 at time of treatment start. 3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR. 4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent. 5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.
Interventions
- OtherNo intervention
Locations (26)
- Stanford UniversityPalo Alto, California
- California Protons Cancer Therapy CenterSan Diego, California
- University of California San FranciscoSan Francisco, California
- University of Florida Health Proton Therapy InstituteJacksonville, Florida
- Emory UniversityAtlanta, Georgia
- Northwestern Medicine Chicago Proton CenterWarrenville, Illinois