Non-invasive Skin Imaging Using Multiphoton Microscopy
University of California, Irvine
Summary
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.
Description
This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) and a MPM imaging system developed at BLI: Fast Large Area Multiphoton Exoscope (FLAME) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies. Any biopsies will be performed by the health care provider as a standard of care procedure.
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Male or Female all age groups * Ability to understand and carry out subject instructions Exclusion Criteria: * Pregnant women
Interventions
- DeviceMultiphoton microscopy-based tomograph.
non-invasive optical biopsy
Location
- Beckman Laser Institute Medical ClinicIrvine, California