University of Wisconsin, Madison
The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.
The aim of this study is to determine if functional muscle stimulation, in addition to non-invasive neurostimulation through the tongue (TDU), directed by electroencephalogram (EEG) output, can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as measured by functional magnetic resonance imaging (fMRI). Adult stroke patients with upper extremity motor impairments (henceforth "experimental group"), healthy controls, and participants with risk factors for stroke, without upper extremity impairment (allowing them to serve as controls for patients with uppe…
Inclusion Criteria (Experimental Group): * Stroke patients with persistent upper extremity (UE) deficits Inclusion Criteria (Control Group 1) * Stroke patients without UE impairments * Participants with risk factors for stroke * healthy controls * No known neurologic, psychiatric or developmental disability Inclusion Criteria (Control Group 2) * Stroke patients with persistent upper extremity (UE) deficits * Moderate upper extremity (dominant right hand affected) impairment (score of 1 or 2 on the motor sub-component of the NIH stroke scale (NIHSS) and ARAT score 20-45) * No upper extr…
FES uses low energy electrical pulses to artificially generate body movements in individuals with muscle paralysis. FES can be used to generate muscle contraction in otherwise paralyzed limbs to restore function.
These assessments will include measures of upper extremity motor assessments, standard stroke scales, and measures of activities of daily living.
A functional magnetic resonance image will be collected.
EEG electrodes will be attached to the participant's scalp using a standard, commercially available electrode cap. Proper electrode placement is made according to the international 10-20 system, ensuring complete electrode coverage over sensorimotor cortex.
RecoveriX is a brain driven rehabilitation system for stroke patients that pairs mental activities with motor functions.
10 week delay before intervention
Arctuva estimate
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