A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
Massachusetts General Hospital
Summary
We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.
Eligibility
- Age range
- 20–75 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: Group I includes healthy subjects with normal appearing corneas, normal topography and pachymetry. Group II includes patients diagnosed as having mild, moderate or advanced keratoconus by our ophthalmology expert on the basis of topography and pachymetry. Group III includes healthy subjects who have undergone LASIK surgery in the past 12 months without complications. Inclusion criteria include normal post-operative topography and pachymetry. Group IV includes patients (age 20 - 60) who have undergone LASIK surgery at least 12 months before the study imaging and have been d…
Interventions
- ProcedureBrillouin imaging
Location
- Massachusetts General HospitalBoston, Massachusetts