Core Biopsies of Breast Tumor Tissue Repository
University of Southern California
Summary
This research trial establishes a breast tumor tissue repository from core biopsies. Collecting breast tissue from core biopsies may allow doctors to learn more about the biology of breast cancer and to analyze proteins, genes, and other components of tumor cells. It may also allow doctors to conduct future studies to help understand how breast cancer grows and how it responds to different types of therapy. This will help doctors develop better breast cancer therapies and better tests to help make treatment decisions.
Description
PRIMARY OBJECTIVES: I. To develop a baseline and serial breast cancer core biopsy repository within the University of Southern California (USC)/Norris Comprehensive Cancer Center Women's Cancer Program. II. To develop and maintain a secure clinical database of relevant demographic, clinical, pathologic and longitudinal outcome characteristics of the samples to be banked. III. To have an efficient process for the distribution of de-identified samples from the bank to researchers with institutional review board (IRB)-approved protocols or exemptions for the study of breast cancer-related ques…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Known or suspected breast cancer * Known or suspected metastatic solid tumor that originated in the breast per the patient's medical history Exclusion Criteria: * Inability to sign informed consent * Known bleeding disorder * Use of anticoagulant medications (heparin, warfarin, etc.) within one week prior to biopsy * Use of antiplatelet medications (aspirin, clopidogrel, etc.) within one week prior to biopsy
Interventions
- Othercytology specimen collection procedure
Correlative studies
Location
- USC Norris Comprehensive Cancer CenterLos Angeles, California