University of Florida
Create a database with selected medical information on infants born with hypoxic-ischemic encephalopathy (HIE). In addition, the following samples will be collected in a bio-repository for future studies: blood, urine, and buccal samples.
The purpose of this study is to create a detailed medical and sample database of infants born with HIE. Both the medical information and the samples are de-identified. Any future studies performed with the data and samples will receive Institutional Review Board (IRB) approval.
Inclusion Criteria: * Gestational Age greater than or equal to 35 weeks gestation * Birth weight greater than or equal to 1.8 kg * Less than or equal to 6 hours since insult occurred * Severe hypoxic-ischemic encepholopathy (HIE) Exclusion Criteria: * Presence of lethal chromosomal abnormalities * Severe IUGR * Significant intracranial hemorrhage with a large intracranial hemorrhage (Grade III or intraparenchymal echodensity (Grade IV))
blood, urine, buccal samples and medical data collected
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