Improving Bladder Function in SCI by Neuromodulation
University of California, Los Angeles
Summary
This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury.
Description
This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury. Neuromodulation will be in the form of transcutaneous electrical stimulation and/or magnetic stimulation.
Eligibility
- Age range
- 18–45 years
- Sex
- Male
- Healthy volunteers
- No
Inclusion Criteria: 1. Male 18-45 years; 2. At least 1 year post-injury; 3. Non-progressive SCI at C2-T8 (non-conus injury); 4. Motor Complete ASIA (A or B); 5. Neurogenic bladder requiring clean intermittent straight catheterization; 6. Able to attend twice weekly testing sessions for 6 months. 7. Have intact lower extremity anatomy and able to use lower extremity for assistive standing and stepping. Exclusion Criteria: 1. History of autonomic dysreflexia; 2. Ventilator dependency; 3. Musculoskeletal dysfunction, unhealed fracture, pressure ulcer, active infection; 4. Clinically significan…
Interventions
- DeviceElectromagnetic Neuromodulation
Electromagnetic stimulation to neuromodulate the spinal cord in the context of spinal cord injury.
Location
- University of California, Los AngelesLos Angeles, California