Mayo Clinic
This study is designed to determine if individual patients with HIV infection have been cured of the infection. To do this, antiretroviral therapy is discontinued under close medical supervision and the patient monitored over time for reactivation of infection.
Inclusion Criteria * Age ≥ 18 years * HIV-1 infected with the potential to have been cured of infection in the course of routine clinical care in the opinion of the treating physician and study team * Have an undetectable plasma HIV-1 RNA and undetectable proviral DNA on suppressive antiretroviral therapy on at least two consecutive measures for at least 6 months * Able and willing to either abstain from sexual activity or use barrier contraceptives during the ATI * Negative serum β-HCG pregnancy test in women with childbearing potential * Have the ability to give appropriate informed consent…
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