Patient-Derived Models Tissue Procurement Protocol for the National Cancer Institute (NCI)
National Cancer Institute LAO
Summary
This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.
Description
PRIMARY OBJECTIVE: I. To procure biologic tissues and materials to generate preclinical models of cancer. OUTLINE: This is an observational study. Tumor tissue and blood samples are procured during procedures that are required for the patients' clinical management and will be stored via xenograft (transplant to another species) models or in vitro cell culture for future analysis.
Eligibility
- Age range
- 0+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients older than 2 months of age who are being evaluated, treated, or enrolled in a clinical trial for cancer at participating sites * Patients with a histologically or cytologically confirmed diagnosis of cancer * Patients without histologically or cytologically confirmed diagnosis of cancer, but for whom approval has been requested and received from the coordinating site study coordinator * Requests for coordinating site approval should only be made if the patient's existing work-up at the time of the request demonstrates a combination of two or more of the follo…
Interventions
- OtherCytology Specimen Collection Procedure
Procurement of tissue and blood samples
Locations (140)
- University of Alabama at Birmingham Cancer CenterBirmingham, Alabama
- Mercy Hospital Fort SmithFort Smith, Arkansas
- PCR OncologyArroyo Grande, California
- City of Hope Comprehensive Cancer CenterDuarte, California
- USC / Norris Comprehensive Cancer CenterLos Angeles, California
- UCHealth University of Colorado HospitalAurora, Colorado