Microvascular VCA Transplantation
NYU Langone Health
Summary
The purpose of this study is to see if an investigational surgery that transfers tissue from a non-living donor to living individual will help restore greater function, appearance, and sensation to the hand and forearm areas of individuals who have suffered traumatic injury to the hand and forearm. This procedure is called a hand allotransplantation or "hand transplant". This study will also collect data on how patients do during and after having a hand transplant from a nonliving donor. Recovery and outcomes will be observed through clinical exams, x-rays, blood and tissue tests, and other associated evaluations at all follow up visits.
Description
The subject will be selected as a possible participant in this study because s/he has suffered traumatic amputation to the hand and s/he has identified that s/he is interested in having a hand transplant as an alternative to continued care using conventional prostheses. Investigators will evaluate subjects between the ages of 18 and 60 who are missing tissue from an area of the hand and forearm. After obtaining consent, several pre-transplant screening procedures and evaluations will be completed. This data will be utilized to determine recipient eligibility and selection for placement onto th…
Eligibility
- Age range
- 18–60 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Candidates may be male or female patients between the ages of 18 and 60 who are missing all or part of one or both hands and forearms * Must be HIV negative at the time of transplant * Crossmatch is negative between donor and recipient * Women who are of child bearing potential must have a negative pregnancy test (urine test is acceptable) within 48 hours of transplant and agree to use reliable contraception for one year following transplant * Subjects must give written informed consent * Subjects who are poor candidates for prosthesis and eligible for hand transplant -…
Interventions
- ProcedureHand Transplantation
microvascular VCA transplant
Location
- NYU Langone Ambulatory Care CenterNew York, New York