Measurement of Energy Metabolism in Infants: BabyEE Pilot
Pennington Biomedical Research Center
Summary
The purpose of this study is to measure energy expenditure during the first 3 months of life in infants.
Description
This study intends to establish the feasibility of undertaking comprehensive metabolic phenotyping in infants. The overarching aim is to complete a prospective assessment of energy expenditure in the new infant metabolic chamber approximately one week apart to determine the accuracy and precision of infant protocols related to energy metabolism (sleeping metabolic rate, resting metabolic rate, diet-induced thermogenesis) and physical activity. This cross-sectional study will answer the following questions: 1. What is the test re-test reliability of measuring energy expenditure (sleeping metab…
Eligibility
- Age range
- 0–0 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Healthy, full-term infant * Aged 1 month (28 days) to 3 months (12 weeks, 6 days) at the first visit * Exclusively fed breast milk and/or infant formula * Willing to accept doubly-labeled water Exclusion Criteria: * Unable to complete 3 clinic visits within about 14 days at Pennington Biomedical Research Center * Born preterm (\< 37 weeks gestation) * Congenital abnormality or disability * Gastric reflux * Acute illness within 7 days of the study (fever, diarrhea) * Use of medications to treat a chronic condition (does not include use of vitamin supplements or PRN medi…
Location
- Pennington Biomedical Research CenterBaton Rouge, Louisiana