Testicular Tissue Cryopreservation for Fertility Preservation in Males Facing Fertility Threatening Diagnoses or Treatment Regimens
Mayo Clinic
Summary
This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.
Description
Testicular tissue cryopreservation is currently considered experimental but offers the only opportunity for fertility preservation in pre-pubescent boys faced with a fertility threatening diagnosis or treatment plan. After completion of study intervention, patients are followed up at 1-week post-surgery and then yearly thereafter.
Eligibility
- Age range
- 0–17 years
- Sex
- Male
- Healthy volunteers
- No
Inclusion Criteria: (All inclusion criteria must be met.) * Be male 0-17 years of age * Meet at least one of the following four conditions: * Be scheduled to undergo surgery, chemotherapy, drug treatment and/or radiation for the treatment or prevention of a medical condition or malignancy with risk of causing permanent and complete loss of subsequent testicular function. Risk categories based on treatment regimens are indicated below. Investigators will utilize three sources to calculate risk: 1. "Fertile Hope - Risks of Azoospermia" brochure that details typical agents and treatment regim…
Interventions
- ProcedureTesticular tissue cryopreservation
Testicular tissue will be removed
Location
- Mayo Clinic in RochesterRochester, Minnesota