Research Contact Registry for Members of the Amish and Mennonite Communities
University of Pittsburgh
Summary
The purpose of this registry is to find members of the Plain Community who are interested in participating in future medical research studies. Having a registry makes it easier to contact and offer study participation to individuals who are appropriate for a new research study based on their own and their family medical history. Studies will focus on increasing knowledge about disorders affecting those who are Amish and Mennonite.
Description
The Amish and Mennonite communities of western Pennsylvania are unique because they are isolated both geographically and socially. These groups originally migrated as a small group from Europe. Since this first settlement there have been additional migration events within North America that have resulted in many distinct communities. These events lead to genetic founder effects, genetic bottleneck effects and virtually zero genetic inflow. The result has been an increased burden of genetic disease on these vulnerable communities. Specific founder genes explain the prevalence of different genet…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Amish and Mennonite men and women age 18 or older * Amish and Mennonite children with the permission of a parent Exclusion Criteria: * Amish and Mennonite men and woman age 18 or older who do not speak English * Those who are not Amish or Mennonite
Location
- Children's Hospital of PittsburghPittsburgh, Pennsylvania