Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
University of Colorado, Denver
Summary
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages. By using x-ray analysis, a new low dose x-ray system (EOS) can be used to evaluate the whole body to see changes in the bone structure over time. Subjects will be asked to undertake one x-ray analysis of their whole body skeletal structure. There will be 25 male and 25 female subjects per decade. The averaging of the measured skeletal parameters will provide information on changes over time generating a standardized expectation of general changes in skeletal structure as participants age.
Description
Current techniques of advanced spinal surgery allow physicians to correct complex spinal deformity to nearly any alignment desired. The investigators ability to analyze spino-pelvic alignment has evolved concurrently; however, the investigators goals in deformity correction are still not completely understood. With increasing ability to assess whole body alignment, the investigators must establish a baseline for the "normal" population inclusive of age related changes. the investigators hypothesis is that global body alignment will vary based on sex and progressively vary with age. The goal o…
Eligibility
- Age range
- 21–85 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Males and females age 21-85 without a history of spine surgery. Exclusion Criteria: * History of spine or neural axis surgery * History of cancer with or without metastatic disease * Connective tissue, rheumatologic (or other inflammatory arthropathies), or neurologic disorders * History of knee replacement surgery, as these may have contractures causing unexpected changes in alignment * Severe osteoarthritis of the hips/knees/ankles * Spondylitis * Compression fractures or other trauma of the spinal column * Previous trauma/fractures of the pelvis whether or not surge…
Interventions
- RadiationEOS imaging
The EOS imaging system will be utilized to obtain full-body radiographs in frontal and sagittal projections obtained in the upright standing position. Measurements will include a coronal plumb-line, sagittal vertebral axis (SVA), external auditory meatus plumb-line, cervical lordosis, thoracic kyphosis, lumbar lordosis, hip flexion/extension, knee flexion/extension, ankle flexion/extension, T1 tilt, T1 spino-pelvic instance, acetabular index, pelvic tilt (PT), pelvic incidence (PI), and sacral slope (SS).
Location
- University of Coloardo DenverAurora, Colorado