University of Alabama at Birmingham
A pilot study to evaluate feasibility of enrollment of patients in an intervention to improve neurocognitive function in hematopoietic cell transplantation (HCT) survivors using the cognitive training Lumosity program. In addition, patients' interest in receiving information regarding genetic risk of cognitive impairment post-HCT will be measured.
The investigators propose using an "off-the-shelf" product - Lumosity (http://www.lumosity.com/) - an online cognitive training program, to address the cognitive impairment in outpatient HCT survivors. The program offers over 60 tasks in game-like format that cover the main cognitive domains: processing speed, working memory, and executive function. Training will involve a daily session of 5 training tasks for 12 weeks. Each time the patient is logged in for a session, a customized report will be generated by the Lumosity program to capture performance information. Ideally, targeting the inte…
Inclusion Criteria: * ≥ 21 years old at time of allogeneic HCT performed at UAB * Outpatient and between 3 and 6 months post HCT * English speaking * Possess access to an internet-connected home computer Exclusion criteria: * History of pre-existing neurological disorder or documented major psychiatric disorder; significant auditory, visual, or motor impairments * Participated in neuropsychological intervention within the past 6 months * History of color blindness
Computer-based online cognitive training program using the Lumosity cognitive training program.
Computer-based online cognitive training program using the Lumosity cognitive training program. The control group will receive the intervention after a waiting period of 12 weeks.
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