The SUDC Registry and Research Collaborative
NYU Langone Health
Summary
The purpose is to increase the understanding of the characteristics, circumstances, medical histories and pathologies of children from ages 11 months through 18 years who have died suddenly and unexpectedly, and in some instances, without explanation. The SUDC Registry and Research Collaborative will analyze cases of sudden unexpected deaths in these children to understand risk factors and causes, and develop preventative measures.
Description
* Review the child's death, medical and family history by our study pathologists (including forensic, pediatric, cardiac and neuropathologists) to determine whether a possible, probable or definite cause of death can be identified and whether additional studies might be helpful in determining a specific cause of death. * For case investigations that are open/active, the registry offers cardiac pathology, and neuroimaging/neuropathology consultations. * For those cases determined to be unexplained/undetermined- access to genetic analysis (whole exome sequencing) when viable samples are availabl…
Eligibility
- Age range
- 0–100 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: Retrospective SUDC Cases * 11months to 18 years of age. * Subjects whose cause of death was sudden and unexplained-"Postinfancy SIDS," "Sudden Death of Childhood," "Undetermined," "Late SIDS," a vague description of symptoms of "undetermined etiology," or a diagnosis acknowledged to be speculative by the prosecting pathologist * If the retrospective case has banked DNA specimens. Prospective SUDC Cases * SUDC cases, parents and eligible family members from 11months-100 years of age. * SUDC Subjects whose death was sudden and unexplained after the initial autopsy, and in…
Interventions
- OtherBiospecimin Collection
Location
- New York University School of MedicineNew York, New York